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Oxidation of microbial iron-sulfur centers by the myeloperoxidase-H2O2-halide antimicrobial system.

Myeloperoxidase, H2O2, and a halide (chloride, bromide, or iodide) form a potent microbicidal system that contributes to the antimicrobial activity of neutrophils. The mechanism of toxicity is not completely understood. Powerful oxidants are formed that presumably attack the microbe at a variety of...

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Bibliografiske detaljer
Main Authors: Rosen, H, Klebanoff, S J
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC261335/
https://ncbi.nlm.nih.gov/pubmed/2982737
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