Neural Precursors Derived from Embryonic Stem Cells, but Not Those from Fetal Ventral Mesencephalon, Maintain the Potential to Differentiate into Dopaminergic Neurons After Expansion In Vitro

Neural precursors (NPs) derived from ventral mesencephalon (VM) normally generate dopaminergic (DA) neurons in vivo but lose their potential to differentiate into DA neurons during mitogenic expansion in vitro, hampering their efficient use as a transplantable and experimental cell source. Because e...

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Bibliographic Details
Main Authors: Chung, Sangmi, Shin, Byoung-Soo, Hwang, Michelle, Lardaro, Thomas, Kang, Un Jung, Isacson, Ole, Kima, Kwang-Soo
Format: Artigo
Language:Inglês
Published: 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613224/
https://ncbi.nlm.nih.gov/pubmed/16543488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2005-0558
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