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The Mechanism of S(N)2 Disulfide Bond Cleavage by Phosphorous Nucleophiles. Implications for Biochemical Disulfide Reducing Agents

The B3LYP variant of DFT has been used to study the mechanism of S-S bond scission in dimethyl disulfide by phosphorus nucleophile, trimethylphospine (TMP). The reaction is highly endothermic in the gas phase and requires significant external stabilization of the charged products. DFT calculations (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dmitrenko, Olga, Thorpe, Colin, Bach, Robert D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613176/
https://ncbi.nlm.nih.gov/pubmed/17914842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo071271w
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