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Recql5 Plays an Important Role in DNA Replication and Cell Survival after Camptothecin Treatment

Disruption of replication can lead to loss of genome integrity and increase of cancer susceptibility in mammals. Thus, a replication impediment constitutes a formidable challenge to these organisms. Recent studies indicate that homologous recombination (HR) plays an important role in suppressing gen...

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Autors principals: Hu, Yiduo, Lu, Xincheng, Zhou, Guangjin, Barnes, Ellen L., Luo, Guangbin
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613109/
https://ncbi.nlm.nih.gov/pubmed/18987339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0565
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