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The OGF–OGFr Axis Utilizes the p16(INK4a) and p21(WAF1/CIP1) Pathways to Restrict Normal Cell Proliferation
Opioid growth factor (OGF) is an endogenous opioid peptide ([Met(5)]enkephalin) that interacts with the OGF receptor (OGFr) and serves as a tonically active negative growth factor in cell proliferation of normal cells. To clarify the mechanism by which OGF inhibits cell replication in normal cells,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613082/ https://ncbi.nlm.nih.gov/pubmed/18923142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-07-0681 |
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