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The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer

BACKGROUND: Pancreatic cancer is the 4th leading cause of death from cancer in the U.S. The opioid growth factor (OGF; [Met(5)]-enkephalin) and the OGF receptor form an inhibitory growth regulatory system involved in the pathogenesis and treatment of pancreatic cancer. The OGF-OGFr axis influences t...

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Autores principales: Cheng, Fan, McLaughlin, Patricia J, Verderame, Michael F, Zagon, Ian S
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253554/
https://ncbi.nlm.nih.gov/pubmed/18190706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-5
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