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Fluorinated phenylcyclopropylamines. Part 5: Effects of electron withdrawing or donating aryl substituents on the inhibition of monoamine oxidases A and B by 2-aryl-2-fluoro-cyclopropylamines

A series of racemic, diastereoisomeric aryl cyclopropylamines substituted with fluorine in the 2-position and electron donating and electron withdrawing groups on the aromatic ring have been prepared. These represent analogues of the classic MAO inhibitor tranylcypromine (trans-2-phenylcyclopropylam...

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Autors principals: Hruschka, Svenja, Rosen, Thomas C., Yoshida, Shinichi, Kirk, Kenneth L., Fröhlich, Roland, Wibbeling, Birgit, Haufe, Günter
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613070/
https://ncbi.nlm.nih.gov/pubmed/18640844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.06.048
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