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Persistent Hypomethylation in the Promoter of Nucleosomal Binding Protein 1 (Nsbp1) Correlates with Overexpression of Nsbp1 in Mouse Uteri Neonatally Exposed to Diethylstilbestrol or Genistein

Neonatal exposure of CD-1 mice to diethylstilbestrol (DES) or genistein (GEN) induces uterine adenocarcinoma in aging animals. Uterine carcinogenesis in this model is ovarian dependent because its evolution is blocked by prepubertal ovariectomy. This study seeks to discover novel uterine genes whose...

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Autori principali: Tang, Wan-Yee, Newbold, Retha, Mardilovich, Katerina, Jefferson, Wendy, Cheng, Robert Y. S., Medvedovic, Mario, Ho, Shuk-Mei
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613067/
https://ncbi.nlm.nih.gov/pubmed/18669593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0682
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