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The T-cell receptor repertoire of regulatory T cells

The CD4(+) CD25(+) regulatory population of T cells (Treg cells), which expresses the forkhead family transcription factor (Foxp3), is the key component of the peripheral tolerance mechanism that protects us from a variety of autoimmune diseases. Experimental evidence shows that Treg cells recognize...

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Autori principali: Pacholczyk, Rafal, Kern, Joanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612558/
https://ncbi.nlm.nih.gov/pubmed/19128356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02992.x
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