Tumour necrosis factor (TNF)-α primes murine neutrophils when triggered via formyl peptide receptor-related sequence 2, the murine orthologue of human formyl peptide receptor-like 1, through a process involving the type I TNF receptor and subcellular granule mobilization

Neutrophil granulocytes play an important role in innate host defence against microbial invasions and they are also the key effector cells in mediating host tissue damage. These functions often rely on the production of reactive oxygen species (ROS) from the membrane-bound NADPH-oxidase system. The...

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Autores principales: Önnheim, Karin, Bylund, Johan, Boulay, Francois, Dahlgren, Claes, Forsman, Huamei
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2008
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612554/
https://ncbi.nlm.nih.gov/pubmed/18710405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02873.x
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