Multivesicular bodies in intestinal epithelial cells: responsible for MHC class II-restricted antigen processing and origin of exosomes

In normal conditions intestinal epithelial cells (IECs) constitutively stimulate regulatory CD4(+) T cells. However, in Crohn's disease (CD), this major histocompatibility complex (MHC) class II-restricted antigen presentation results in stimulation of proinflammatory CD4(+) T cells. We hypothe...

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Detalhes bibliográficos
Main Authors: Büning, Jürgen, von Smolinski, Dorthe, Tafazzoli, Kianush, Zimmer, Klaus-Peter, Strobel, Stephan, Apostolaki, Maria, Kollias, George, Heath, Joan K, Ludwig, Diether, Gebert, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612547/
https://ncbi.nlm.nih.gov/pubmed/18710406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02864.x
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