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New Role for the Protein Tyrosine Phosphatase DEP-1 in Akt Activation and Endothelial Cell Survival

Functional inactivation of the protein tyrosine phosphatase DEP-1 leads to increased endothelial cell proliferation and failure of vessels to remodel and branch. DEP-1 has also been proposed to contribute to the contact inhibition of endothelial cell growth via dephosphorylation of vascular endothel...

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Autori principali: Chabot, Catherine, Spring, Kathleen, Gratton, Jean-Philippe, Elchebly, Mounib, Royal, Isabelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612487/
https://ncbi.nlm.nih.gov/pubmed/18936167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01374-08
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