A completely synthetic toxoid vaccine containing Escherichia coli heat-stable toxin and antigenic determinants of the heat-labile toxin B subunit.

The immunodeterminant regions of the Escherichia coli heat-labile toxin B subunit were identified by determining the antigenicity, by using enzyme-linked immunosorbent assays, of synthetically produced peptides corresponding to various segments of its 124-amino-acid sequence. The addition of the 18-...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Houghten, R A, Engert, R F, Ostresh, J M, Hoffman, S R, Klipstein, F A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1985
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC261245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2581899/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.48.3.735-740.1985
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