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Overexpression of Interleukin-15 Compromises CD4-Dependent Adaptive Immune Responses against Herpes Simplex Virus 2

Interleukin-15 (IL-15) is necessary for the development and function of NK/NKT cells and the maintenance of naive and memory CD8(+) T cells. In the absence of IL-15, protective innate immunity is not available; however, a functional adaptive immune response against vaginal herpes simplex virus 2 (HS...

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Autores principales: Gill, Navkiran, Ashkar, Ali A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612378/
https://ncbi.nlm.nih.gov/pubmed/19004955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01282-08
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