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VP22 of Herpes Simplex Virus 1 Promotes Protein Synthesis at Late Times in Infection and Accumulation of a Subset of Viral mRNAs at Early Times in Infection

VP22, encoded by the U(L)49 gene, is one of the most abundant proteins of the herpes simplex virus 1 (HSV-1) tegument. In the present study we show VP22 is required for optimal protein synthesis at late times in infection. Specifically, in the absence of VP22, viral proteins accumulated to wild-type...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Duffy, Carol, Mbong, Ekaette F., Baines, Joel D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612369/
https://ncbi.nlm.nih.gov/pubmed/18987147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02245-07
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