Deletion of the First Cysteine-Rich Region of the Varicella-Zoster Virus Glycoprotein E Ectodomain Abolishes the gE and gI Interaction and Differentially Affects Cell-Cell Spread and Viral Entry

Varicella-zoster virus (VZV) glycoprotein E (gE) is the most abundant glycoprotein in infected cells and, in contrast to those of other alphaherpesviruses, is essential for viral replication. The gE ectodomain contains a unique N-terminal region required for viral replication, cell-cell spread, and...

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Detalhes bibliográficos
Main Authors: Berarducci, Barbara, Rajamani, Jaya, Reichelt, Mike, Sommer, Marvin, Zerboni, Leigh, Arvin, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612333/
https://ncbi.nlm.nih.gov/pubmed/18945783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00913-08
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