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Antiviral Activity of the Zinc Ionophores Pyrithione and Hinokitiol against Picornavirus Infections

We have discovered two metal ion binding compounds, pyrithione (PT) and hinokitiol (HK), that efficiently inhibit human rhinovirus, coxsackievirus, and mengovirus multiplication. Early stages of virus infection are unaffected by these compounds. However, the cleavage of the cellular eukaryotic trans...

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Detalhes bibliográficos
Principais autores: Krenn, B. M., Gaudernak, E., Holzer, B., Lanke, K., Van Kuppeveld, F. J. M., Seipelt, J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612303/
https://ncbi.nlm.nih.gov/pubmed/18922875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01543-08
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