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Inhibition of Polyprotein Processing and RNA Replication of Human Rhinovirus by Pyrrolidine Dithiocarbamate Involves Metal Ions

Pyrrolidine dithiocarbamate (PDTC) is an antiviral compound that was shown to inhibit the replication of human rhinoviruses (HRVs), poliovirus, and influenza virus. To elucidate the mechanism of PDTC, the effects on the individual steps of the infection cycle of HRV were investigated. PDTC did not i...

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Hlavní autoři: Krenn, B. M., Holzer, B., Gaudernak, E., Triendl, A., van Kuppeveld, F. J., Seipelt, J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280194/
https://ncbi.nlm.nih.gov/pubmed/16254325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13892-13899.2005
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