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Inhibition of Polyprotein Processing and RNA Replication of Human Rhinovirus by Pyrrolidine Dithiocarbamate Involves Metal Ions

Pyrrolidine dithiocarbamate (PDTC) is an antiviral compound that was shown to inhibit the replication of human rhinoviruses (HRVs), poliovirus, and influenza virus. To elucidate the mechanism of PDTC, the effects on the individual steps of the infection cycle of HRV were investigated. PDTC did not i...

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Bibliografiset tiedot
Päätekijät: Krenn, B. M., Holzer, B., Gaudernak, E., Triendl, A., van Kuppeveld, F. J., Seipelt, J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280194/
https://ncbi.nlm.nih.gov/pubmed/16254325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.13892-13899.2005
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