Pyrrolidine Dithiocarbamate Reduces Coxsackievirus B3 Replication through Inhibition of the Ubiquitin-Proteasome Pathway

Coxsackievirus B3 (CVB3) is one of the most common pathogens for viral myocarditis. The lack of effective therapeutics for CVB3-caused viral diseases underscores the importance of searching for antiviral compounds. Pyrrolidine dithiocarbamate (PDTC) is an antioxidant and is recently reported to inhi...

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Detalhes bibliográficos
Main Authors: Si, Xiaoning, McManus, Bruce M., Zhang, Jingchun, Yuan, Ji, Cheung, Caroline, Esfandiarei, Mitra, Suarez, Agripina, Morgan, Andrew, Luo, Honglin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143712/
https://ncbi.nlm.nih.gov/pubmed/15956547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8014-8023.2005
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