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CS-8958, a Prodrug of the New Neuraminidase Inhibitor R-125489, Shows Long-Acting Anti-Influenza Virus Activity

Two neuraminidase (NA) inhibitors, zanamivir (Relenza) and oseltamivir phosphate (Tamiflu), have been licensed for the treatment of and prophylaxis against influenza. In this paper, the new potent NA inhibitor R-125489 is reported for the first time. R-125489 inhibited the NA activities of various t...

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Bibliografiske detaljer
Main Authors: Yamashita, Makoto, Tomozawa, Takanori, Kakuta, Masayo, Tokumitsu, Akane, Nasu, Hatsumi, Kubo, Shuku
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612152/
https://ncbi.nlm.nih.gov/pubmed/18955520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00333-08
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