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Laninamivir Prodrug CS-8958, a Long-Acting Neuraminidase Inhibitor, Shows Superior Anti-Influenza Virus Activity after a Single Administration

Two neuraminidase (NA) inhibitors, zanamivir (Relenza) and oseltamivir phosphate (Tamiflu), have been licensed for use for the treatment and prophylaxis of influenza. We have reported on laninamivir (code name, R-125489), a novel neuraminidase inhibitor, and have discovered that the laninamivir prod...

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Bibliografische gegevens
Hoofdauteurs: Kubo, Shuku, Tomozawa, Takanori, Kakuta, Masayo, Tokumitsu, Akane, Yamashita, Makoto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825999/
https://ncbi.nlm.nih.gov/pubmed/20047917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01311-09
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