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Laninamivir Prodrug CS-8958, a Long-Acting Neuraminidase Inhibitor, Shows Superior Anti-Influenza Virus Activity after a Single Administration

Two neuraminidase (NA) inhibitors, zanamivir (Relenza) and oseltamivir phosphate (Tamiflu), have been licensed for use for the treatment and prophylaxis of influenza. We have reported on laninamivir (code name, R-125489), a novel neuraminidase inhibitor, and have discovered that the laninamivir prod...

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Main Authors: Kubo, Shuku, Tomozawa, Takanori, Kakuta, Masayo, Tokumitsu, Akane, Yamashita, Makoto
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825999/
https://ncbi.nlm.nih.gov/pubmed/20047917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01311-09
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