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Laninamivir Prodrug CS-8958, a Long-Acting Neuraminidase Inhibitor, Shows Superior Anti-Influenza Virus Activity after a Single Administration

Two neuraminidase (NA) inhibitors, zanamivir (Relenza) and oseltamivir phosphate (Tamiflu), have been licensed for use for the treatment and prophylaxis of influenza. We have reported on laninamivir (code name, R-125489), a novel neuraminidase inhibitor, and have discovered that the laninamivir prod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kubo, Shuku, Tomozawa, Takanori, Kakuta, Masayo, Tokumitsu, Akane, Yamashita, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825999/
https://ncbi.nlm.nih.gov/pubmed/20047917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01311-09
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