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Effect of thiol-activated toxins (streptolysin O, alveolysin, and theta toxin) on the generation of leukotrienes and leukotriene-inducing and -metabolizing enzymes from human polymorphonuclear granulocytes.

The generation of leukotrienes (LTC4, LTD4, LTE4, and LTB4; 12-epi-LTB4 isomer) from human granulocytes by thiol-activated toxins (streptolysin O, alveolysin from Bacillus alvei, and theta toxin from Clostridium perfringens) is described. The release occurs under noncytolytic conditions. Although LT...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Bremm, K D, König, W, Pfeiffer, P, Rauschen, I, Theobald, K, Thelestam, M, Alouf, J E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC261157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2866160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.50.3.844-851.1985
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