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Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans.

Acapsular (Cap-) mutants of Cryptococcus neoformans var. neoformans that produce melanin (Mel+) on diphenol media at 30 degrees C but not at 37 degrees C were found to be avirulent for mice. Compared with wild-type isolates, the mutants had a lower rate of L-3,4-dihydroxyphenylalanine uptake at 37 d...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Kwon-Chung, K J, Rhodes, J C
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1986
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC261090/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3079732/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.51.1.218-223.1986
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