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Encapsulation and melanin formation as indicators of virulence in Cryptococcus neoformans.

Acapsular (Cap-) mutants of Cryptococcus neoformans var. neoformans that produce melanin (Mel+) on diphenol media at 30 degrees C but not at 37 degrees C were found to be avirulent for mice. Compared with wild-type isolates, the mutants had a lower rate of L-3,4-dihydroxyphenylalanine uptake at 37 d...

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Autors principals: Kwon-Chung, K J, Rhodes, J C
Format: Artigo
Idioma:Inglês
Publicat: 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC261090/
https://ncbi.nlm.nih.gov/pubmed/3079732
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