Treatment of alveolar macrophages with cytochalasin D inhibits uptake and subsequent growth of Legionella pneumophila.

Legionella pneumophila multiplied rapidly in guinea pig and rat alveolar macrophages but failed to grow when phagocytic activity was inhibited by pretreatment with 0.5 or 1.0 microgram of cytochalasin D per ml. Attachment was not inhibited by cytochalasin D. No extracellular multiplication occurred...

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Publicado en:	Infect Immun
Autores principales:	Elliott, J A, Winn, W C
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1986
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC261061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3941000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.51.1.31-36.1986
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