Treatment of alveolar macrophages with cytochalasin D inhibits uptake and subsequent growth of Legionella pneumophila.

Legionella pneumophila multiplied rapidly in guinea pig and rat alveolar macrophages but failed to grow when phagocytic activity was inhibited by pretreatment with 0.5 or 1.0 microgram of cytochalasin D per ml. Attachment was not inhibited by cytochalasin D. No extracellular multiplication occurred...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Infect Immun
Prif Awduron:	Elliott, J A, Winn, W C
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 1986
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC261061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3941000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.51.1.31-36.1986
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