Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioural, and neurotoxic effects of methamphetamine

N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) lesions of the locus coeruleus (LC), the major brain noradrenergic nucleus, exacerbate the damage to nigrostriatal dopamine (DA) terminals caused by the psychostimulant methamphetamine (METH). However, because noradrenergic terminals contain other...

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Main Authors: Weinshenker, David, Ferrucci, Michela, Busceti, Carla L., Biagioni, Francesca, Lazzeri, Gloria, Liles, L. Cameron, Lenzi, Paola, Murri, Luigi, Paparelli, Antonio, Fornai, Francesco
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610530/
https://ncbi.nlm.nih.gov/pubmed/18042179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.05145.x
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