Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence

Motivation: A challenging problem after a genome-wide association study (GWAS) is to balance the statistical evidence of genotype–phenotype correlation with a priori evidence of biological relevance. Results: We introduce a method for systematically prioritizing single nucleotide polymorphisms (SNPs...

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Autores principales: Saccone, Scott F., Saccone, Nancy L., Swan, Gary E., Madden, Pamela A. F., Goate, Alison M., Rice, John P., Bierut, Laura J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
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Original Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610477/
https://ncbi.nlm.nih.gov/pubmed/18565990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn315
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