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Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence
Motivation: A challenging problem after a genome-wide association study (GWAS) is to balance the statistical evidence of genotype–phenotype correlation with a priori evidence of biological relevance. Results: We introduce a method for systematically prioritizing single nucleotide polymorphisms (SNPs...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2610477/ https://ncbi.nlm.nih.gov/pubmed/18565990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn315 |
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