Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-β/BMP signaling during tooth and palate development

Smad4 is a central intracellular effector of TGF-β signaling. Smad-independent TGF-β pathways, such as those mediated by p38 MAPK, have been identified in cell culture systems, but their in vivo functional mechanisms remain unclear. In this study, we investigated the role of TGF-β signaling in tooth...

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Detaylı Bibliyografya
Asıl Yazarlar: Xu, Xun, Han, Jun, Ito, Yoshihiro, Bringas, Pablo, Deng, Chuxia, Chai, Yang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610417/
https://ncbi.nlm.nih.gov/pubmed/18694570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.06.004
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