Statins Activate Human PPARα Promoter and Increase PPARα mRNA Expression and Activation in HepG2 Cells

Statins increase peroxisome proliferator-activated receptor α (PPARα) mRNA expression, but the mechanism of this increased PPARα production remains elusive. To examine the regulation of PPARα production, we examined the effect of 7 statins (atorvastatin, cerivastatin, fluvastatin, pitavastatin, prav...

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Detalhes bibliográficos
Main Authors: Seo, Makoto, Inoue, Ikuo, Ikeda, Masaaki, Nakano, Takanari, Takahashi, Seiichiro, Katayama, Shigehiro, Komoda, Tsugikazu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610383/
https://ncbi.nlm.nih.gov/pubmed/19125197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/316306
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