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Orchestrating anaphase and mitotic exit: separase cleavage and localisation of Slk19

Anaphase in budding yeast is triggered by cleavage of the central subunit, Scc1, of the chromosomal cohesin complex by the protease separase. Here we show that separase also cleaves the kinetochore-associated protein Slk19 at anaphase onset. Separase activity is further required for proper localisat...

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Detalhes bibliográficos
Main Authors: Sullivan, Matthew, Lehane, Christine, Uhlmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610359/
https://ncbi.nlm.nih.gov/pubmed/11533655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb0901-771
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