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Orchestrating anaphase and mitotic exit: separase cleavage and localisation of Slk19

Anaphase in budding yeast is triggered by cleavage of the central subunit, Scc1, of the chromosomal cohesin complex by the protease separase. Here we show that separase also cleaves the kinetochore-associated protein Slk19 at anaphase onset. Separase activity is further required for proper localisat...

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Autores principales: Sullivan, Matthew, Lehane, Christine, Uhlmann, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610359/
https://ncbi.nlm.nih.gov/pubmed/11533655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb0901-771
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