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Light-induced translocation of cyclic-GMP phosphodiesterase on rod disc membranes in rat retina
PURPOSE: Cyclic GMP phosphodiesterase (PDE) is the light-regulated effector enzyme of vertebrate rods. Upon photo-activation of rhodopsin followed by activation of transducin/GTP, PDE rapidly hydrolyzes 3′, 5′-cyclic GMP (cGMP) to 5′-GMP, which results in closure of cGMP-dependent ion channels and g...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Molecular Vision
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2610287/ https://ncbi.nlm.nih.gov/pubmed/19112528 |
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