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Pretreatment with the Gram-positive Bacterial Cell Wall Molecule Peptidoglycan Improves Bacterial Clearance and Decreases Inflammation and Mortality in Mice Challenged with Staphylococcus aureus
OBJECTIVE: To determine whether tolerance and enhancement of innate immune function can be induced by the gram-positive cell wall component peptidoglycan (PGN). DESIGN: Controlled, in vivo laboratory study SUBJECTS: Male mice, 8-12 wks (C57BL6/J; C3H/HeJ; B6.129-Tlr2(tm1kir)/J) INTERVENTIONS: Mice w...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2610268/ https://ncbi.nlm.nih.gov/pubmed/18824898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31818c6fb7 |
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