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Pretreatment with the gram-positive bacterial cell wall molecule peptidoglycan improves bacterial clearance and decreases inflammation and mortality in mice challenged with Pseudomonas aeruginosa

The objective of this study was to determine if inflammatory tolerance and enhancement of innate immune function could be induced by the gram-positive cell wall component peptidoglycan (PGN). Male mice (C57BL6/J or C3H/HeJ, 8-12 weeks of age) were given intraperitoneal injections of 1mg PGN on 2 con...

詳細記述

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書誌詳細
主要な著者: Murphey, E.D., Sherwood, E.R.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603308/
https://ncbi.nlm.nih.gov/pubmed/18678270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2008.07.021
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