ΔFosB Mediates Epigenetic Desensitization of the c-fos Gene After Chronic Amphetamine Exposure

The molecular mechanisms underlying the transition from recreational drug use to chronic addiction remain poorly understood. One molecule implicated in this process is ΔFosB, a transcription factor that accumulates in striatum after repeated drug exposure and mediates sensitized behavioral responses...

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Autors principals: Renthal, William, Carle, Tiffany L., Maze, Ian, Covington, Herbert E., Truong, Hoang-Trang, Alibhai, Imran, Kumar, Arvind, Montgomery, Rusty L., Olson, Eric N., Nestler, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610249/
https://ncbi.nlm.nih.gov/pubmed/18632938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1043-08.2008
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