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Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin.

Injection of D-galactosamine sensitizes mice many thousand-fold to the lethal action of endotoxin (lipopolysaccharide [LPS]). Comparable sensitization was practically absent in LPS-resistant C3H/HeJ mice, which after D-galactosamine treatment were about 500,000 times less sensitive to LPS lethality...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Freudenberg, M A, Keppler, D, Galanos, C
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260982/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3949385/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.51.3.891-895.1986
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