Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin.

Injection of D-galactosamine sensitizes mice many thousand-fold to the lethal action of endotoxin (lipopolysaccharide [LPS]). Comparable sensitization was practically absent in LPS-resistant C3H/HeJ mice, which after D-galactosamine treatment were about 500,000 times less sensitive to LPS lethality...

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Bibliographic Details
Main Authors: Freudenberg, M A, Keppler, D, Galanos, C
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC260982/
https://ncbi.nlm.nih.gov/pubmed/3949385
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