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Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes

The ability of small interfering RNA (siRNA) to regulate gene expression has potential therapeutic applications, but its use is limited by inefficient delivery. Triggered release of adsorbed poly(ethylene glycol) (PEG)-b-polycation polymers from pH-dependent (PD) liposomes enables protection from im...

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Detalhes bibliográficos
Main Authors: Auguste, Debra T., Furman, Kay, Wong, Andrew, Fuller, Jason, Armes, Steven P., Deming, Timothy J., Langer, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2608725/
https://ncbi.nlm.nih.gov/pubmed/18601962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2008.06.004
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