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The barrier to enantiomerization of N-Boc-2-lithiopyrrolidine: the effect of chiral and achiral diamines

(−)-Sparteine and TMEDA dramatically lower both enthalpy and entropy of activation for the barrier to enantiomerization of N-Boc-2-lithiopyrrolidine in diethyl ether, whereas N,N'-diisopropylbispidine has little effect. The entropy of activation for enantiomerization is zero in the presence of...

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Detalhes bibliográficos
Main Authors: Yousaf, Taher I., Williams, Roger L., Coldham, Iain, Gawley, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607545/
https://ncbi.nlm.nih.gov/pubmed/18399412
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