Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues

BACKGROUND: The Nonsense-Mediated mRNA Decay (NMD) pathway detects and degrades mRNAs containing premature termination codons, thereby preventing the accumulation of potentially detrimental truncated proteins. Intertissue variation in the efficiency of this mechanism has been suggested, which could...

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Autores principales: Zetoune, Almoutassem B, Fontanière, Sandra, Magnin, Delphine, Anczuków, Olga, Buisson, Monique, Zhang, Chang X, Mazoyer, Sylvie
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607305/
https://ncbi.nlm.nih.gov/pubmed/19061508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-83
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