Efficacy assessment of sustained intraperitoneal paclitaxel therapy in a murine model of ovarian cancer using bioluminescent imaging

We evaluated the pre-clinical efficacy of a novel intraperitoneal (i.p.) sustained-release paclitaxel formulation (PTX(ePC)) using bioluminescent imaging (BLI) in the treatment of ovarian cancer. Human ovarian carcinoma cells stably expressing the firefly luciferase gene (SKOV3(Luc)) were injected i...

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Autori principali: Vassileva, V, Moriyama, E H, De Souza, R, Grant, J, Allen, C J, Wilson, B C, Piquette-Miller, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
Soggetti:
Translational Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607231/
https://ncbi.nlm.nih.gov/pubmed/19034272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604803
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