Optimal drug delivery for intraperitoneal paclitaxel (PTX) in murine model

BACKGROUND: Repeated intraperitoneal (IP) administration of paclitaxel (PTX) with concurrent systemic chemotherapy is clinically effective for the treatment of peritoneal metastases (PM) from gastric cancer. However, it is unclear how biochemical modifications may affect the pharmacokinetics and bio...

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Detalhes bibliográficos
Publicado no:Pleura Peritoneum
Main Authors: Kitayama, Joji, Ishigami, Hironori, Yamaguchi, Hironori, Yamada, Jun, Soma, Daisuke, Miyato, Hideyo, Kamei, Takao, Lefor, Alan Kawarai, Sata, Naohiro
Formato: Artigo
Idioma:Inglês
Publicado em: De Gruyter 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405031/
https://ncbi.nlm.nih.gov/pubmed/30911637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/pp-2017-0002
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