Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex

gp130 is a shared receptor for at least nine cytokines, and can signal either as a homodimer, or as a heterodimer with Leukemia Inhibitory Factor Receptor (LIF-R). Here we biophysically and structurally characterize the full-length, transmembrane form of a quaternary cytokine receptor complex consis...

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Bibliographic Details
Main Authors: Skiniotis, Georgios, Lupardus, Patrick, Martick, Monika, Walz, Thomas, Garcia, K. Christopher
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607196/
https://ncbi.nlm.nih.gov/pubmed/18775332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.08.011
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