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Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes
An RNA-based gene silencing pathway that protects bacteria and archaea from viruses and other genome invaders is hypothesized to arise from guide RNAs encoded by CRISPR loci and proteins encoded by the cas genes. CRISPR loci contain multiple short invader-derived sequences separated by short repeats...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2607076/ https://ncbi.nlm.nih.gov/pubmed/19141480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1742908 |
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