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CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation
Cytoplasmic polyadenylation element-binding protein (CPEB) stimulates polyadenylation and translation in germ cells and neurons. Here, we show that CPEB-regulated translation is essential for the senescence of human diploid fibroblasts. Knockdown of CPEB causes skin and lung cells to bypass the M1 c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2607074/ https://ncbi.nlm.nih.gov/pubmed/19141477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1697808 |
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