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CPEB regulation of human cellular senescence, energy metabolism, and p53 mRNA translation

Cytoplasmic polyadenylation element-binding protein (CPEB) stimulates polyadenylation and translation in germ cells and neurons. Here, we show that CPEB-regulated translation is essential for the senescence of human diploid fibroblasts. Knockdown of CPEB causes skin and lung cells to bypass the M1 c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Burns, David M., Richter, Joel D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607074/
https://ncbi.nlm.nih.gov/pubmed/19141477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1697808
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