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Identification of a Cigarette Smoke–Responsive Region in the Distal MMP-1 Promoter

Tobacco-related diseases are leading causes of death worldwide, and many are associated with expression of matrix metalloproteinase-1 (MMP-1). We have reported extracellular signal–regulated kinase (ERK)1/2-dependent induction of MMP-1 by cigarette smoke in lung epithelial cells. Our objectives were...

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Detalhes bibliográficos
Principais autores: Mercer, Becky A., Wallace, Alison M., Brinckerhoff, Constance E., D'Armiento, Jeanine M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606945/
https://ncbi.nlm.nih.gov/pubmed/18617682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0310OC
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