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Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process

PURPOSE: Cigarette smoke is the major risk factor associated with the development of chronic obstructive pulmonary disease (COPD). Recent studies propose a link between endoplasmic reticulum (ER) stress and emphysema, demonstrated by increased ER stress markers under smoking conditions. Here, we inv...

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Main Authors: Geraghty, Patrick, Wallace, Alison, D’Armiento, Jeanine M
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119106/
https://ncbi.nlm.nih.gov/pubmed/21697995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S19599
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